Pregnancy comes with a long list of do’s and don’ts — from what to eat to what medications to avoid. One of the most common questions expectant mothers have is: “Can I take ibuprofen while pregnant?” The answer is not a simple yes or no. It depends on the stage of your pregnancy and your individual health needs.
What Is Ibuprofen?
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to reduce pain, inflammation, and fever. Brand names include Advil, Motrin, and Nurofen. While it’s effective for many common ailments, its safety during pregnancy is a bit more complicated.

Ibuprofen and Early Pregnancy (First and Second Trimester)
Some studies suggest that occasional use of ibuprofen in the first and second trimester may not be harmful, but most healthcare professionals recommend avoiding it unless absolutely necessary and advised by your doctor.
Why the caution? Even in early pregnancy, there’s some evidence that NSAIDs may be linked to a slightly increased risk of miscarriage or certain developmental issues. Paracetamol (acetaminophen) is generally considered a safer alternative for pain relief in early pregnancy.
Third Trimester: A Definite No
After 20 weeks of pregnancy — and especially in the third trimester — ibuprofen is strongly discouraged. Here’s why:
- It can lead to premature closure of the fetal ductus arteriosus, a vital blood vessel in the baby’s heart.
- There’s a higher risk of low amniotic fluid (oligohydramnios).
- It may delay or prolong labor.
Due to these risks, health authorities like the U.S. FDA and many international medical organizations recommend avoiding ibuprofen after 20 weeks of pregnancy unless no safer alternatives are available and the benefits outweigh the risks.
What to Take Instead?
If you’re pregnant and experiencing pain, acetaminophen (paracetamol) is typically the go-to option. It’s widely considered safe for all stages of pregnancy when taken as directed. However, even with acetaminophen, you should use the lowest effective dose for the shortest possible time.
When to Talk to Your Doctor
If you are dealing with chronic pain, inflammation, or fever during pregnancy, don’t self-medicate. Always consult your OB-GYN or healthcare provider. They can recommend safer alternatives or refer you to a specialist if needed.
Bottom Line
- Avoid ibuprofen in the third trimester.
- Use with caution (and only if advised) in early pregnancy.
- Opt for acetaminophen/paracetamol as a safer alternative.
- Always consult your doctor before taking any medication during pregnancy.
Pregnancy can be uncomfortable, and pain relief is sometimes necessary — but safety comes first. When in doubt, your healthcare provider is your best source of guidance.
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